Efficacy of Cellular Treatments

Because the field of regenerative medicine is still relatively new, the number of clinical studies to assess its efficacy is still growing.

But as more and more patients agree to participate in clinical studies, the body of evidence to support the power of cellular treatments to treat orthopedic conditions is becoming more robust.

Consider some of this data from various studies related to different regenerative treatment options:

• Platelet Rich Plasma (PRP)
  A study of patients who received platelet rich plasma (PRP) treatments for spinal disc herniation revealed that participants who received intradiscal PRP showed significant improvements in their function and pain scores over eight weeks compared to those in the control group who did not receive PRP. Moreover, the PRP patients maintained significant improvements for at least one year.[i]
• Adipose (Fat) Stem Cell Treatments
  Patients in a study who were treated with the Lipogems® autologous adipose (fat) stem cell treatment for knee osteoarthritis revealed that their pain while at rest and while moving was significantly decreased at six weeks, six months and 12 months following treatment.  No serious adverse events were reported.[ii]
• Bone Marrow Aspirate Concentrate (BMAC)
  A comprehensive review of several different studies on the effectiveness of autologous bone marrow aspirate concentrate to treat lumbar disc degeneration revealed that nearly all patients in the various studies reported statistically significant improvement in pain and function even after 12 months post-treatment.[iii]
• Endoret® Platelet Rich Growth Factors (PRGF
  In a study of athletes suffering from high ankle sprains, those who received Endoret PRGF (plasma rich growth factors) via ultrasound-guided injections had a shorter return-to-play window, improved re-stabilization of the joint and less long-term residual pain than those in the control group.[iv]

As is true of any medical treatment, overall effectiveness is impacted by a number of factors, including extent and degree of injury or damage, the patient’s overall health, age and in some cases, genetics. But these studies of different kinds of regenerative treatments reveal that employing the body’s own healing properties can be an effective, non-surgical option for a variety of orthopedic conditions.

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